Various extracts of TwHF (Tripterygium wilfordii Hook F. or Thunder God Vine) has been widely used in China for hundreds of years for various symptoms. The chloroform-methanol extract of the roots of TwHF (mTGV) has been investigated as a potential treatment for autoimmune diseases.
Over the past 30 years, extracts of TwHF (Thunder God Vine) have become a standard therapy for rheumatoid arthritis in China. Recently, extracts of TwHF were tested in the West and shown good efficacy.
Ranking by the SUCRA values showed that TwHF had the greatest probability for being the best treatment option according to ACR 20 and ACR 50, and the highest probability to be in the second ranking position after leflunomide (Arava) according to ACR 70.
More importantly, the result of the current analysis found that TwHF (mTGV) is safe, causing no more drug-emergent withdrawals than the placebo.
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