Patients stopped their treatments 4 weeks before entering the trial. Some patients took anti inflammatory drugs such as Prednisone not over 7.5 mg per day and/or NSAIDs. They were required to take the same stable dosage throughout the trial.
The most common side effect was diarrhea. It caused 1 patient in the high-dose group to withdraw from the trial. The trial is on a very small number of persons, but the results are nonetheless highly significant.
I quote: “The ethanol/ethyl acetate extract of TWHF (mTGV) shows therapeutic benefit in patients with treatment-refractory RA. At therapeutic dosages, the TWHF extract was well tolerated by most patients in this study.”
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