The clinical trial was a double blind study, meaning that none of the participants involved knew which treatment (placebo or blarcamesine) each was receiving. The participants were treated for 14 weeks, during which they were clinically assessed to determine if the treatment was having an effect.
After analysing the results, the investigators reported that blarcamesine treatment led to a significant improvement in cognitive test scores, but also an 11 point increase in motor scores in the treated group (as opposed to a 3.5 point decline in the placebo group). In the press release, the company has indicated that with these positive results they are seeking regulatory guidance on how to proceed with their clinical development of blarcamesine.
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